Bone marrow is the spongy material inside long bones, pelvis,
clavicle that produces all blood cells – red blood cells (RBCs), white blood cells (WBCs) and platelets. Bone marrow also contains raw materials that are important for manufacturing of blood cells, such as iron, vitamin B12, and folic acid.
What is bone marrow examination?
A bone marrow examination usually consists of two separate tests
that are often done at the same time; a bone marrow aspiration that obtains a sample of the liquid portion of the bone marrow from which special tests can be done, and a bone marrow biopsy that obtains a sample of the solid material. The most common site for a bone marrow biopsy is the large pelvic bone near the hip (posterior iliac crest), but a sample may also be taken from the sternum (breastbone), or, in infants, the shin bone (tibia).
When is bone marrow examination indicated?
• Unexplained abnormal increase/decrease in any of the blood cells
• Diagnosis, workup and follow up of blood cancers like leukemia and lymphoma, or for some cancers spreading to involve bone marrow.
• For work up of fever of unknown origin
• Some rare genetic syndromes